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Identification of Transcription Factor AML-1 Binding Site Upstream of Human Cytomegalovirus UL111A Gene

Human cytomegalovirus (HCMV) interleukin-10 (hcmvIL-10), encoded by HCMV UL111A gene, is a homolog of human IL-10. It exerts immunomodulatory effects that allow HCMV to evade host defense mechanisms. However, the exact mechanism underlying the regulation of hcmvIL-10 expression is not well understoo...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaoqun, Gao, Yan, Zhang, Qi, Liu, Yanqing, Peng, Ying, Fu, Miao, Ji, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320089/
https://www.ncbi.nlm.nih.gov/pubmed/25658598
http://dx.doi.org/10.1371/journal.pone.0117773