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Diminished mTOR signaling: a common mode of action for endocrine longevity factors
Since the initial observation that a calorie-restricted (CR) diet can extend rodent lifespan, many genetic and pharmaceutical interventions that also extend lifespan in mammals have been discovered. The mechanism by which CR and these other interventions extend lifespan is the subject of significant...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer International Publishing
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320218/ https://www.ncbi.nlm.nih.gov/pubmed/25674466 http://dx.doi.org/10.1186/2193-1801-3-735 |