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Myelodysplasia is in the niche: novel concepts and emerging therapies

Myelodysplastic syndromes (MDSs) represent clonal disorders mainly of the elderly that are characterized by ineffective hematopoiesis and an increased risk of transformation into acute myeloid leukemia. The pathogenesis of MDS is thought to evolve from accumulation and selection of specific genetic...

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Detalles Bibliográficos
Autores principales: Bulycheva, E, Rauner, M, Medyouf, H, Theurl, I, Bornhäuser, M, Hofbauer, L C, Platzbecker, U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320287/
https://www.ncbi.nlm.nih.gov/pubmed/25394715
http://dx.doi.org/10.1038/leu.2014.325