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Ins1(Cre) knock-in mice for beta cell-specific gene recombination

AIMS/HYPOTHESIS: Pancreatic beta cells play a central role in the control of glucose homeostasis by secreting insulin to stimulate glucose uptake by peripheral tissues. Understanding the molecular mechanisms that control beta cell function and plasticity has critical implications for the pathophysio...

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Detalles Bibliográficos
Autores principales: Thorens, Bernard, Tarussio, David, Maestro, Miguel Angel, Rovira, Meritxell, Heikkilä, Eija, Ferrer, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320308/
https://www.ncbi.nlm.nih.gov/pubmed/25500700
http://dx.doi.org/10.1007/s00125-014-3468-5