Knockdown of MVK does not lead to changes in NALP3 expression or activation

BACKGROUND: Mutations in the Mevalonate Kinase gene (MVK) are causes of a rare autoinflammatory disease: Mevalonate Kinase Deficiency and its more acute manifestation, Mevalonic Aciduria. The latter is characterized, among other features, by neuroinflammation, developmental delay and ataxia, due to...

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Detalles Bibliográficos
Autores principales: Celsi, Fulvio, Piscianz, Elisa, Romano, Maurizio, Crovella, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320511/
https://www.ncbi.nlm.nih.gov/pubmed/25663823
http://dx.doi.org/10.1186/s12950-015-0048-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320511/
https://www.ncbi.nlm.nih.gov/pubmed/25663823
http://dx.doi.org/10.1186/s12950-015-0048-5

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