Cargando…
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
Although great progress has been made in the characterization of off-target effects of engineered nucleases, sensitive and unbiased genome-wide methods for the detection of off-target cleavage events and potential collateral damage are still lacking. Here we describe a linear amplification–mediated...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320661/ https://www.ncbi.nlm.nih.gov/pubmed/25503383 http://dx.doi.org/10.1038/nbt.3101 |