Carbamoyl Radical-Mediated Synthesis and Semipinacol Rearrangement of β-Lactam Diols

In an approach to the biologically important 6-azabicyclo[3.2.1]octane ring system, the scope of the tandem 4-exo-trig carbamoyl radical cyclization—dithiocarbamate group transfer reaction to ring-fused β-lactams is evaluated. β-Lactams fused to five-, six-, and seven-membered rings are prepared in...

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Detalles Bibliográficos
Autores principales: Betou, Marie, Male, Louise, Steed, Jonathan W, Grainger, Richard S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320754/
https://www.ncbi.nlm.nih.gov/pubmed/24711140
http://dx.doi.org/10.1002/chem.201304982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320754/
https://www.ncbi.nlm.nih.gov/pubmed/24711140
http://dx.doi.org/10.1002/chem.201304982

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