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Carbamoyl Radical-Mediated Synthesis and Semipinacol Rearrangement of β-Lactam Diols

In an approach to the biologically important 6-azabicyclo[3.2.1]octane ring system, the scope of the tandem 4-exo-trig carbamoyl radical cyclization—dithiocarbamate group transfer reaction to ring-fused β-lactams is evaluated. β-Lactams fused to five-, six-, and seven-membered rings are prepared in...

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Detalles Bibliográficos
Autores principales:	Betou, Marie, Male, Louise, Steed, Jonathan W, Grainger, Richard S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2014
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320754/ https://www.ncbi.nlm.nih.gov/pubmed/24711140 http://dx.doi.org/10.1002/chem.201304982

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