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The Protective Effect of Lacidipine on Myocardial Remodeling Is Mediated by the Suppression in Expression of GPR78 and CHOP in Rats

Lacidipine (LAC) is now widely used for the treatment of hypertension and further can prevent cardiac hypertrophy and remodeling. However, the underlying mechanism has not been fully understood. In this study, we examined the protective effects of LAC on cardiac remodeling in spontaneously hypertens...

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Detalles Bibliográficos
Autores principales: Ge, Yingxiao, Li, Gang, Liu, Baoxin, Guo, Huixin, Wang, Dongzhi, Jie, Qiqiang, Che, Wenliang, Hou, Lei, Wei, Yidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320802/
https://www.ncbi.nlm.nih.gov/pubmed/25688281
http://dx.doi.org/10.1155/2015/945076