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OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo

BACKGROUND: Ubiquitination is a highly dynamic and reversible process with a central role in cell homeostasis. Deregulation of several deubiquitinating enzymes has been linked to tumor development but their specific role in prostate cancer progression remains unexplored. METHODS: RNAi screening was...

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Detalles Bibliográficos
Autores principales: Iglesias-Gato, Diego, Chuan, Yin-Choy, Jiang, Ning, Svensson, Charlotte, Bao, Jing, Paul, Indranil, Egevad, Lars, Kessler, Benedikt M, Wikström, Pernilla, Niu, Yuanjie, Flores-Morales, Amilcar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320819/
https://www.ncbi.nlm.nih.gov/pubmed/25623341
http://dx.doi.org/10.1186/s12943-014-0280-2