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OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo
BACKGROUND: Ubiquitination is a highly dynamic and reversible process with a central role in cell homeostasis. Deregulation of several deubiquitinating enzymes has been linked to tumor development but their specific role in prostate cancer progression remains unexplored. METHODS: RNAi screening was...
Autores principales: | Iglesias-Gato, Diego, Chuan, Yin-Choy, Jiang, Ning, Svensson, Charlotte, Bao, Jing, Paul, Indranil, Egevad, Lars, Kessler, Benedikt M, Wikström, Pernilla, Niu, Yuanjie, Flores-Morales, Amilcar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320819/ https://www.ncbi.nlm.nih.gov/pubmed/25623341 http://dx.doi.org/10.1186/s12943-014-0280-2 |
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