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Prognostic and predictive role of CXCR4, IGF-1R and Ezrin expression in localized synovial sarcoma: is chemotaxis important to tumor response?

BACKGROUND: Synovial sarcoma (SS) is a rare tumor, with dismal survival when metastatic. The role of adjuvant chemotherapy is debated. New prognostic and predictive factors are needed. METHODS: We reviewed patients with localized SS; SS18-SSX fusion transcript presence was confirmed by FISH and RT-P...

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Detalles Bibliográficos
Autores principales: Palmerini, Emanuela, Benassi, Maria Serena, Quattrini, Irene, Pazzaglia, Laura, Donati, Davide, Benini, Stefania, Gamberi, Gabriella, Gambarotti, Marco, Picci, Piero, Ferrari, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320838/
https://www.ncbi.nlm.nih.gov/pubmed/25613038
http://dx.doi.org/10.1186/s13023-014-0222-5