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Lentiviral-Mediated Silencing of Farnesyl Pyrophosphate Synthase through RNA Interference in Mice

Farnesyl pyrophosphate synthase (FPPS) plays a vital role in the mevalonate pathway and has been shown to be involved in hypertrophy and cardiovascular diseases. Lentivirus-mediated RNA interference (RNAi) to knock down a gene of interest has become a promising new tool for the establishment of tran...

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Detalles Bibliográficos
Autores principales: Yang, Jian, Zhao, Chen-Ze, Chen, Bin, Chen, Fei, Han, Jie, Hu, Shen-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320928/
https://www.ncbi.nlm.nih.gov/pubmed/25688370
http://dx.doi.org/10.1155/2015/914026