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Altered DNA methylation status of human brain derived neurotrophis factor gene could be useful as biomarker of depression

Brain-derived neurotrophic factor (BDNF) is involved in the survival, development, and synaptic plasticity of neurons. BDNF is believed to be associated with the pathophysiology of psychiatric disorders. Several studies have suggested the relevance of DNA methylation in its promoter region with depr...

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Detalles Bibliográficos
Autores principales: Song, Yixuan, Miyaki, Koichi, Suzuki, Tomoko, Sasaki, Yasuharu, Tsutsumi, Akizumi, Kawakami, Norito, Shimazu, Akihito, Takahashi, Masaya, Inoue, Akiomi, Kan, Chiemi, Kurioka, Sumiko, Shimbo, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321058/
https://www.ncbi.nlm.nih.gov/pubmed/24801253
http://dx.doi.org/10.1002/ajmg.b.32238