Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence

The mode of action human relevance (MOA/HR) framework increases transparency in systematically considering data on MOA for end (adverse) effects and their relevance to humans. This framework continues to evolve as experience increases in its application. Though the MOA/HR framework is not designed t...

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Detalles Bibliográficos
Autores principales: Meek, M E (Bette), Palermo, Christine M, Bachman, Ammie N, North, Colin M, Jeffrey Lewis, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321063/
https://www.ncbi.nlm.nih.gov/pubmed/24777878
http://dx.doi.org/10.1002/jat.2984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321063/
https://www.ncbi.nlm.nih.gov/pubmed/24777878
http://dx.doi.org/10.1002/jat.2984

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