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High-Risk Microgranular Acute Promyelocytic Leukemia with a Five-Way Complex Translocation Involving PML-RARA

Acute promyelocytic leukemia (APL) is classically characterized by chromosomal translocation (15;17), resulting in the PML-RARA fusion protein leading to disease. Here, we present a case of a 50-year-old man who presented with signs and symptoms of acute leukemia with concern for APL. Therapy was im...

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Detalles Bibliográficos
Autores principales: Powers, Benjamin, Persons, Diane, Rao, Deepthi, Woodroof, Janet, Lin, Tara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321077/
https://www.ncbi.nlm.nih.gov/pubmed/25692052
http://dx.doi.org/10.1155/2015/343854