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Stretching Fibroblasts Remodels Fibronectin and Alters Cancer Cell Migration

Most investigations of cancer-stroma interactions have focused on biochemical signaling effects, with much less attention being paid to biophysical factors. In this study, we investigated the role of mechanical stimuli on human prostatic fibroblasts using a microfluidic platform that was adapted for...

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Detalles Bibliográficos
Autores principales: Ao, Mingfang, Brewer, Bryson M., Yang, Lijie, Franco Coronel, Omar E., Hayward, Simon W., Webb, Donna J., Li, Deyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321168/
https://www.ncbi.nlm.nih.gov/pubmed/25660754
http://dx.doi.org/10.1038/srep08334