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The pattern of DNA cleavage intensity around indels

Indels (insertions and deletions) are the second most common form of genetic variations in the eukaryotic genomes and are responsible for a multitude of genetic diseases. Despite its significance, detailed molecular mechanisms for indel generation are still unclear. Here we examined 2,656,597 small...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Zhang, Liqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321175/
https://www.ncbi.nlm.nih.gov/pubmed/25660536
http://dx.doi.org/10.1038/srep08333