GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy

Autophagy is a common physiological function in all eukaryotes. The process is induced by depletion of nutrients including amino acids. GADD34 is expressed following DNA damage, ER stresses and amino acid deprivation. Here, we investigated the effects of GADD34 on autophagy and cell activation in ma...

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Detalles Bibliográficos
Autores principales: Ito, Sachiko, Tanaka, Yuriko, Oshino, Reina, Aiba, Keiko, Thanasegaran, Suganya, Nishio, Naomi, Isobe, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321179/
https://www.ncbi.nlm.nih.gov/pubmed/25659802
http://dx.doi.org/10.1038/srep08327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321179/
https://www.ncbi.nlm.nih.gov/pubmed/25659802
http://dx.doi.org/10.1038/srep08327

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