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Intrathecal Delivery of Mesenchymal Stromal Cells Protects the Structure of Altered Perineuronal Nets in SOD1 Rats and Amends the Course of ALS

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder resulting in a lethal outcome. We studied changes in ventral horn perineuronal nets (PNNs) of superoxide dismutase 1 (SOD1) rats during the normal disease course and after the intrathecal application (5 × 10(5) cells) of...

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Detalles Bibliográficos
Autores principales: Forostyak, Serhiy, Homola, Ales, Turnovcova, Karolina, Svitil, Pavel, Jendelova, Pavla, Sykova, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321196/
https://www.ncbi.nlm.nih.gov/pubmed/25113670
http://dx.doi.org/10.1002/stem.1812