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Improved cytotoxic effects of Salmonella-producing cytosine deaminase in tumour cells

In order to increase the cytotoxic activity of a Salmonella strain carrying a salicylate-inducible expression system that controls cytosine deaminase production, we have modified both, the vector and the producer bacterium. First, the translation rates of the expression module containing the Escheri...

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Detalles Bibliográficos
Autores principales: Mesa-Pereira, Beatriz, Medina, Carlos, Camacho, Eva María, Flores, Amando, Santero, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321383/
https://www.ncbi.nlm.nih.gov/pubmed/25227763
http://dx.doi.org/10.1111/1751-7915.12153