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Improved cytotoxic effects of Salmonella-producing cytosine deaminase in tumour cells
In order to increase the cytotoxic activity of a Salmonella strain carrying a salicylate-inducible expression system that controls cytosine deaminase production, we have modified both, the vector and the producer bacterium. First, the translation rates of the expression module containing the Escheri...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321383/ https://www.ncbi.nlm.nih.gov/pubmed/25227763 http://dx.doi.org/10.1111/1751-7915.12153 |