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Effect of genistein on basal jejunal chloride secretion in R117H CF mice is sex and route specific

Cystic fibrosis (CF) results from the loss or reduction in function of the CFTR (cystic fibrosis transmembrane conductance regulatory protein) chloride channel. The third most common CFTR mutation seen clinically is R117H. Genistein, a naturally occurring phytoestrogen, is known to stimulate CFTR fu...

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Detalles Bibliográficos
Autores principales: Rayyan, Esa, Polito, Sarah, Leung, Lana, Bhakta, Ashesh, Kang, Jonathan, Willey, Justin, Mansour, Wasim, Drumm, Mitchell L, Al-Nakkash, Layla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321419/
https://www.ncbi.nlm.nih.gov/pubmed/25674010
http://dx.doi.org/10.2147/CEG.S72111