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Sustained release of vancomycin from novel biodegradable nanofiber-loaded vascular prosthetic grafts: in vitro and in vivo study

This study describes novel biodegradable, drug-eluting nanofiber-loaded vascular prosthetic grafts that provide local and sustained delivery of vancomycin to surrounding tissues. Biodegradable nanofibers were prepared by first dissolving poly(D,L)-lactide-co-glycolide and vancomycin in 1,1,1,3,3,3-h...

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Detalles Bibliográficos
Autores principales: Liu, Kuo-Sheng, Lee, Cheng-Hung, Wang, Yi-Chuan, Liu, Shih-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321605/
https://www.ncbi.nlm.nih.gov/pubmed/25673985
http://dx.doi.org/10.2147/IJN.S78675