Cargando…

Liver-targeted cyclosporine A-encapsulated poly (lactic-co-glycolic) acid nanoparticles inhibit hepatitis C virus replication

Therapeutic options for hepatitis C virus (HCV) infection have been limited by drug resistance and adverse side effects. Targeting the host factor cyclophilin A (CypA), which is essential for HCV replication, offers a promising strategy for antiviral therapy. However, due to its immunosuppressive ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Jyothi, KR, Beloor, Jagadish, Jo, Ara, Nguyen, Minh Nam, Choi, Tae Gyu, Kim, Jin-Hwan, Akter, Salima, Lee, Sang-Kyung, Maeng, Chi Hoon, Baik, Hyung Hwan, Kang, Insug, Ha, Joohun, Kim, Sung Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321639/
https://www.ncbi.nlm.nih.gov/pubmed/25673987
http://dx.doi.org/10.2147/IJN.S74723