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Liver-targeted cyclosporine A-encapsulated poly (lactic-co-glycolic) acid nanoparticles inhibit hepatitis C virus replication
Therapeutic options for hepatitis C virus (HCV) infection have been limited by drug resistance and adverse side effects. Targeting the host factor cyclophilin A (CypA), which is essential for HCV replication, offers a promising strategy for antiviral therapy. However, due to its immunosuppressive ac...
Autores principales: | Jyothi, KR, Beloor, Jagadish, Jo, Ara, Nguyen, Minh Nam, Choi, Tae Gyu, Kim, Jin-Hwan, Akter, Salima, Lee, Sang-Kyung, Maeng, Chi Hoon, Baik, Hyung Hwan, Kang, Insug, Ha, Joohun, Kim, Sung Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321639/ https://www.ncbi.nlm.nih.gov/pubmed/25673987 http://dx.doi.org/10.2147/IJN.S74723 |
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