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cDNA synthesis for BCR-ABL1 detection at the MMR level: the importance of using the appropriate kit

BACKGROUND: The synthesis of complementary DNA (cDNA) for use in the detection of BCR-ABL1 at the Major Molecular Response (MMR) level is a well-established method used by clinical laboratories world-wide. However, the quality of cDNA provides sensitivity challenges and consequently affects the dete...

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Detalles Bibliográficos
Autores principales: Chi, Jianxiang, Pierides, Chryso, Mitsidou, Andrie, Miltiadou, Andri, Gerasimou, Petroula, Costeas, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321704/
https://www.ncbi.nlm.nih.gov/pubmed/25667568
http://dx.doi.org/10.1186/s12575-015-0014-x