Cargando…

Structure of human mitochondrial RNA polymerase elongation complex

The crystal structure of the human mitochondrial RNA polymerase (mtRNAP) transcription elongation complex was determined at 2.65 Å resolution. The structure reveals a 9–base pair hybrid formed between the DNA template and the RNA transcript and one turn of DNA both upstream and downstream of the hyb...

Descripción completa

Detalles Bibliográficos
Autores principales: Schwinghammer, Kathrin, Cheung, Alan C.M., Morozov, Yaroslav I., Agaronyan, Karen, Temiakov, Dmitry, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321815/
https://www.ncbi.nlm.nih.gov/pubmed/24096365
http://dx.doi.org/10.1038/nsmb.2683