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Axonal transport declines with age in two distinct phases separated by a period of relative stability()
Axonal transport is critical for supplying newly synthesized proteins, organelles, mRNAs, and other cargoes from neuronal cell bodies into axons. Its impairment in many neurodegenerative conditions appears likely to contribute to pathogenesis. Axonal transport also declines during normal aging, but...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321880/ https://www.ncbi.nlm.nih.gov/pubmed/25443288 http://dx.doi.org/10.1016/j.neurobiolaging.2014.09.018 |