Cargando…
Axonal transport declines with age in two distinct phases separated by a period of relative stability()
Axonal transport is critical for supplying newly synthesized proteins, organelles, mRNAs, and other cargoes from neuronal cell bodies into axons. Its impairment in many neurodegenerative conditions appears likely to contribute to pathogenesis. Axonal transport also declines during normal aging, but...
Autores principales: | Milde, Stefan, Adalbert, Robert, Elaman, M. Handan, Coleman, Michael P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321880/ https://www.ncbi.nlm.nih.gov/pubmed/25443288 http://dx.doi.org/10.1016/j.neurobiolaging.2014.09.018 |
Ejemplares similares
-
Subcellular Localization Determines the Stability and Axon Protective Capacity of Axon Survival Factor Nmnat2
por: Milde, Stefan, et al.
Publicado: (2013) -
Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport
por: Adalbert, Robert, et al.
Publicado: (2018) -
Axonal trafficking of NMNAT2 and its roles in axon growth and survival in vivo
por: Milde, Stefan, et al.
Publicado: (2013) -
Slow Axonal Transport of Neurofilament Protein in Cultured Neurons
por: Koehnle, Thomas J., et al.
Publicado: (1999) -
Tau phosphorylation affects its axonal transport and degradation
por: Rodríguez-Martín, Teresa, et al.
Publicado: (2013)