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Structure and Assembly Pathway of the Ribosome Quality Control Complex

During ribosome-associated quality control, stalled ribosomes are split into subunits and the 60S-housed nascent polypeptides are poly-ubiquitinated by Listerin. How this low-abundance ubiquitin ligase targets rare stall-generated 60S among numerous empty 60S is unknown. Here, we show that Listerin...

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Detalles Bibliográficos
Autores principales: Shao, Sichen, Brown, Alan, Santhanam, Balaji, Hegde, Ramanujan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321881/
https://www.ncbi.nlm.nih.gov/pubmed/25578875
http://dx.doi.org/10.1016/j.molcel.2014.12.015