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Structure and Assembly Pathway of the Ribosome Quality Control Complex
During ribosome-associated quality control, stalled ribosomes are split into subunits and the 60S-housed nascent polypeptides are poly-ubiquitinated by Listerin. How this low-abundance ubiquitin ligase targets rare stall-generated 60S among numerous empty 60S is unknown. Here, we show that Listerin...
Autores principales: | Shao, Sichen, Brown, Alan, Santhanam, Balaji, Hegde, Ramanujan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321881/ https://www.ncbi.nlm.nih.gov/pubmed/25578875 http://dx.doi.org/10.1016/j.molcel.2014.12.015 |
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