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Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin
Hypochlorous acid added as reagent or generated by the myeloperoxidase (MPO)-H(2)O(2)-Cl(−) system oxidatively modifies brain ether-phospholipids (plasmalogens). This reaction generates a sn2-acyl-lysophospholipid and chlorinated fatty aldehydes. 2-Chlorohexadecanal (2-ClHDA), a prototypic member of...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321883/ https://www.ncbi.nlm.nih.gov/pubmed/25576489 http://dx.doi.org/10.1016/j.bcp.2014.12.017 |