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Epithelial calcium-sensing receptor activation by eosinophil granule protein analog stimulates collagen matrix contraction

BACKGROUND: Eosinophils reside in normal gastrointestinal tracts and increase in disease. Receptors for eosinophil derived granule proteins (EDGPs) have not been identified but highly cationic molecules, similar to eosinophil proteins, bind extracellular calcium-sensing receptors (CaSR). We hypothes...

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Detalles Bibliográficos
Autores principales: Ngo, Peter D., MacLeod, R. John, Mukkada, Vince, Turki, Razan, Furuta, Glenn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321999/
https://www.ncbi.nlm.nih.gov/pubmed/23269116
http://dx.doi.org/10.1038/pr.2012.198