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Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice

Progressive tissue fibrosis is a cause of major morbidity and mortality. Pulmonary fibrosis is an epithelial-mesenchymal disorder in which TGF-β1 plays a central role in pathogenesis. Here we show that follistatin-like 1 (FSTL1) differentially regulates TGF-β and bone morphogenetic protein signaling...

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Detalles Bibliográficos
Autores principales: Dong, Yingying, Geng, Yan, Li, Lian, Li, Xiaohe, Yan, Xiaohua, Fang, Yinshan, Li, Xinxin, Dong, Siyuan, Liu, Xue, Li, Xue, Yang, Xiuhong, Zheng, Xiaohong, Xie, Ting, Liang, Jiurong, Dai, Huaping, Liu, Xinqi, Yin, Zhinan, Noble, Paul W., Jiang, Dianhua, Ning, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322044/
https://www.ncbi.nlm.nih.gov/pubmed/25584011
http://dx.doi.org/10.1084/jem.20121878