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Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient

Neutrophils respond to invading bacteria by adopting a polarized morphology, migrating in the correct direction, and engulfing the bacteria. How neutrophils establish and precisely orient this polarity toward pathogens remains unclear. Here we report that in resting neutrophils, the ERM (ezrin, radi...

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Detalles Bibliográficos
Autores principales: Liu, Xiaowen, Yang, Tao, Suzuki, Koya, Tsukita, Sachiko, Ishii, Masaru, Zhou, Shuping, Wang, Gang, Cao, Luyang, Qian, Feng, Taylor, Shalina, Oh, Myung-Jin, Levitan, Irena, Ye, Richard D., Carnegie, Graeme K., Zhao, Yong, Malik, Asrar B., Xu, Jingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322047/
https://www.ncbi.nlm.nih.gov/pubmed/25601651
http://dx.doi.org/10.1084/jem.20140508