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Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient
Neutrophils respond to invading bacteria by adopting a polarized morphology, migrating in the correct direction, and engulfing the bacteria. How neutrophils establish and precisely orient this polarity toward pathogens remains unclear. Here we report that in resting neutrophils, the ERM (ezrin, radi...
Autores principales: | Liu, Xiaowen, Yang, Tao, Suzuki, Koya, Tsukita, Sachiko, Ishii, Masaru, Zhou, Shuping, Wang, Gang, Cao, Luyang, Qian, Feng, Taylor, Shalina, Oh, Myung-Jin, Levitan, Irena, Ye, Richard D., Carnegie, Graeme K., Zhao, Yong, Malik, Asrar B., Xu, Jingsong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322047/ https://www.ncbi.nlm.nih.gov/pubmed/25601651 http://dx.doi.org/10.1084/jem.20140508 |
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