Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence

A balance between quiescence and proliferation is critical for proper maintenance of the hematopoietic stem cell (HSC) pool. Although a lot is known about hematopoiesis, molecular mechanisms that control HSC quiescence remain largely unknown. The ubiquitin-editing enzyme A20 functions as a central r...

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Detalles Bibliográficos
Autores principales: Nakagawa, Masahiro Marshall, Thummar, Keyur, Mandelbaum, Jonathan, Pasqualucci, Laura, Rathinam, Chozha Vendan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322050/
https://www.ncbi.nlm.nih.gov/pubmed/25624445
http://dx.doi.org/10.1084/jem.20132544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322050/
https://www.ncbi.nlm.nih.gov/pubmed/25624445
http://dx.doi.org/10.1084/jem.20132544

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