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Communication over the Network of Binary Switches Regulates the Activation of A(2A) Adenosine Receptor
Dynamics and functions of G-protein coupled receptors (GPCRs) are accurately regulated by the type of ligands that bind to the orthosteric or allosteric binding sites. To glean the structural and dynamical origin of ligand-dependent modulation of GPCR activity, we performed total ~ 5 μsec molecular...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322061/ https://www.ncbi.nlm.nih.gov/pubmed/25664580 http://dx.doi.org/10.1371/journal.pcbi.1004044 |