Downregulation of Kinesin Spindle Protein Inhibits Proliferation, Induces Apoptosis and Increases Chemosensitivity in Hepatocellular Carcinoma Cells

Background: Kinesin spindle protein (KSP) plays a critical role in mitosis. Inhibition of KSP function leads to cell cycle arrest at mitosis and ultimately to cell death. The aim of this study was to suppress KSP expression by specific small-interfering RNA (siRNA) in Hep3B cells and evaluate its an...

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Detalles Bibliográficos
Autores principales: Doan, Chinh Chung, Doan, Ngoc Trung, Nguyen, Quang Huy, Nguyen, Minh Hoa, Do, Minh Si, Le, Van Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322227/
https://www.ncbi.nlm.nih.gov/pubmed/25605484
http://dx.doi.org/10.6091/ibj.1386.2014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322227/
https://www.ncbi.nlm.nih.gov/pubmed/25605484
http://dx.doi.org/10.6091/ibj.1386.2014

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