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The molecular architecture of dihydropyrindine receptor/L-type Ca(2+) channel complex

Dihydropyridine receptor (DHPR), an L-type Ca(2+) channel complex, plays an essential role in muscle contraction, secretion, integration of synaptic input in neurons and synaptic transmission. The molecular architecture of DHPR complex remains elusive. Here we present a 15-Å resolution cryo-electron...

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Detalles Bibliográficos
Autores principales: Hu, Hongli, Wang, Zhao, Wei, Risheng, Fan, Guizhen, Wang, Qiongling, Zhang, Kaiming, Yin, Chang-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322351/
https://www.ncbi.nlm.nih.gov/pubmed/25667046
http://dx.doi.org/10.1038/srep08370