IER3 is a crucial mediator of TAp73β-induced apoptosis in cervical cancer and confers etoposide sensitivity

Infection with high-risk human papillomaviruses (HPVs) causes cervical cancer. E6 oncoprotein, an HPV gene product, inactivates the major gatekeeper p53. In contrast, its isoform, TAp73β, has become increasingly important, as it is resistant to E6. However, the intracellular signaling mechanisms tha...

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Detalles Bibliográficos
Autores principales: Jin, Hanyong, Suh, Dae-Shik, Kim, Tae-Hyoung, Yeom, Ji-Hyun, Lee, Kangseok, Bae, Jeehyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322356/
https://www.ncbi.nlm.nih.gov/pubmed/25666857
http://dx.doi.org/10.1038/srep08367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322356/
https://www.ncbi.nlm.nih.gov/pubmed/25666857
http://dx.doi.org/10.1038/srep08367

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