Remifentanil added to sufentanil-sevoflurane anesthesia suppresses hemodynamic and metabolic stress responses to intense surgical stimuli more effectively than high-dose sufentanil-sevoflurane alone

BACKGROUND: Even extremely high-doses of the potent opioid, sufentanil, cannot reliably suppress stress responses to intense surgical stimuli such as sternotomy. The chemically related opioid remifentanil with its different pharmacokinetics and binding affinities for delta- and kappa-opioid receptor...

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Detalles Bibliográficos
Autores principales: Bergmann, Ingo, Szabanowski, Torsten, Bräuer, Anselm, Crozier, Thomas A, Bauer, Martin, Hinz, José Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322556/
https://www.ncbi.nlm.nih.gov/pubmed/25670917
http://dx.doi.org/10.1186/1471-2253-15-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322556/
https://www.ncbi.nlm.nih.gov/pubmed/25670917
http://dx.doi.org/10.1186/1471-2253-15-3

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