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Time-resolved gene expression profiling during reprogramming of C/EBPα-pulsed B cells into iPS cells

The reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is lengthy and inefficient. The development of a reprogramming system that allows rapid and synchronous reprogramming to pluripotency is imperative for understanding the mechanism of iPSC formation and for future therapeuti...

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Detalles Bibliográficos
Autores principales: Di Stefano, Bruno, Collombet, Samuel, Graf, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322579/
https://www.ncbi.nlm.nih.gov/pubmed/25977766
http://dx.doi.org/10.1038/sdata.2014.8