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Genome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat

Identification of mechanisms of resistance to histone deacetylase inhibitors, such as vorinostat, is important in order to utilise these anticancer compounds more efficiently in the clinic. Here, we present a dataset containing multiple tiers of stringent siRNA screening for genes that when knocked...

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Detalles Bibliográficos
Autores principales: Falkenberg, Katrina J, Gould, Cathryn M, Johnstone, Ricky W, Simpson, Kaylene J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322586/
https://www.ncbi.nlm.nih.gov/pubmed/25977774
http://dx.doi.org/10.1038/sdata.2014.17