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Modulation of tau phosphorylation by environmental copper

BACKGROUND: The transition metal copper enhances amyloid β aggregation and neurotoxicity, and in models of concomitant amyloid and tau pathology, copper also promotes tau aggregation. Since it is not clear if the effects of environmental copper upon tau pathology are dependent on the presence of pat...

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Detalles Bibliográficos
Autores principales: Voss, Kellen, Harris, Christopher, Ralle, Martina, Duffy, Megan, Murchison, Charles, Quinn, Joseph F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322670/
https://www.ncbi.nlm.nih.gov/pubmed/25671100
http://dx.doi.org/10.1186/2047-9158-3-24