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Extensive amplification of GI-VII-6, a multidrug resistance genomic island of Salmonella enterica serovar Typhimurium, increases resistance to extended-spectrum cephalosporins

GI-VII-6 is a chromosomally integrated multidrug resistance genomic island harbored by a specific clone of Salmonella enterica serovar Typhimurium (S.Typhimurium). It contains a gene encoding CMY-2 β-lactamase (bla(CMY−2)), and therefore contributes to extended-spectrum cephalosporin resistance. To...

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Detalles Bibliográficos
Autores principales: Lee, Ken-ichi, Kusumoto, Masahiro, Sekizuka, Tsuyoshi, Kuroda, Makoto, Uchida, Ikuo, Iwata, Taketoshi, Okamoto, Susumu, Yabe, Kimiko, Inaoka, Takashi, Akiba, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322709/
https://www.ncbi.nlm.nih.gov/pubmed/25713569
http://dx.doi.org/10.3389/fmicb.2015.00078