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Extragenic suppressor mutations in ΔripA disrupt stability and function of LpxA

BACKGROUND: Francisella tularensis is a Gram-negative bacterium that infects hundreds of species including humans, and has evolved to grow efficiently within a plethora of cell types. RipA is a conserved membrane protein of F. tularensis, which is required for growth inside host cells. As a means to...

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Detalles Bibliográficos
Autores principales: Miller, Cheryl N, Steele, Shaun P, Brunton, Jason C, Jenkins, Ronald J, LoVullo, Eric D, Taft-Benz, Sharon A, Romanchuk, Artur, Jones, Corbin D, Dotson, Garry D, Collins, Edward J, Kawula, Thomas H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322802/
https://www.ncbi.nlm.nih.gov/pubmed/25551578
http://dx.doi.org/10.1186/s12866-014-0336-x