Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines

BACKGROUND: Lapatinib is a dual epidermal growth factor receptor (EGFR) and HER2 inhibitor. Overexpression of these receptors is frequently observed in head and neck squamous cell carcinoma (HNSCC). As growing proportion of HNSCC is characterized by human papillomavirus (HPV) infection, we aimed at...

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Detalles Bibliográficos
Autores principales: Fumagalli, Ingrid, Dugue, Delphine, Bibault, Jean Emmanuel, Clémenson, Céline, Vozenin, Marie Catherine, Mondini, Michele, Deutsch, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322874/
https://www.ncbi.nlm.nih.gov/pubmed/25678800
http://dx.doi.org/10.2147/OTT.S68235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322874/
https://www.ncbi.nlm.nih.gov/pubmed/25678800
http://dx.doi.org/10.2147/OTT.S68235

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