CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling

Human ovarian cancer is diagnosed in the late, metastatic stages but the underlying mechanisms remain poorly understood. We report a surprising functional link between CD151-α3β1 integrin complexes and the malignancy of serous-type ovarian cancer. Analyses of clinical specimens indicate that CD151 e...

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Detalles Bibliográficos
Autores principales: Baldwin, Lauren A., Hoff, John T., Lefringhouse, Jason, Zhang, Michael, Jia, Changhe, Liu, Zeyi, Erfani, Sonia, Jin, Hongyan, Xu, Mei, She, Qing-Bai, van Nagell, John R., Wang, Chi, Chen, Li, Plattner, Rina, Kaetzel, David M., Luo, Jia, Lu, Michael, West, Dava, Liu, Chunming, Ueland, Fred R., Drapkin, Ronny, Zhou, Binhua P., Yang, Xiuwei H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322965/
https://www.ncbi.nlm.nih.gov/pubmed/25356755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322965/
https://www.ncbi.nlm.nih.gov/pubmed/25356755

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